Publishers look for works that appeal to the needs of their clients. If your work featured an unusual instrumentation would you sacrifice the color so your work could be published? Last time I checked pieces written for tenor, celesta, vibes, 2 marimbas, and cello were not on the top seller list of classical publications. Would you rescore the work for SATB and piano instead? Or if you had a violin, clarinet, bassoon, and tuba piece would you rescore the work for string quartet or full orchestra? These are just some examples.