They are audio Cd, so they contain tracks with different notes played for each track. You have to convert each track in wav format and then you can slice each note, create multiple wavs and assign them to keymap. All loops can be created only with audio software and for each single note.
You definitely want "sampler formatted" sample CDs if you have that sampler (if you have Kontakt or Giga). All of the programming, including mapping samples across keyboard keys has been done for you.
The Audio CDs would be just that -- .wav files. I could be wrong, but I think there would only be loop points in them if they were "Acidized" wavs.
Many GIGA libraries also take advantage of "key-switching" -- one can switch between sample variations "on the fly" by pressing a different piano key.
If you are specifically talking about the Spectrasonics "groove" libraries, the AKAI versions have what they call "Groove Control" which are midi files with associated "chopped up" samples, which allow you to play the grooves back at different tempos (like Propellerheads ReCycle). Finally, the upcoming Stylus RMX is supposed to allow you to import Groove Control libraries into it.