Starts with Pythagoras, moves through the inner ear, the nervous system, and crows, taking some time to reach Joplin, and the creation of a new piano mechanism to detune the strings: essentially (I think) about the best way to detune the two and three strings per note on a piano to achieve "honk" on a piano. With examples at the bottom of the article.

I'm going to play with this some--take some notes when I have time (ha!), detune them using his calculations, and then layer them on top of each other to see if I can mess up a good piano sample. I have a question, though--do all the strings hit by a single hammer ring with the same volume when struck?