I prefer Cubse Vst 24 as my number one Seqencer.
I\'m able to hard disk record at the same time with cubase up to 32 tracks of audio.
check these songs they were done on one computer with Vst and GigaSampler by Lac lc Shira. I use gina and sblive as my sound cards. http://www.northernsounds.com/demos/dance/lac/itsup.mp3