Is it recommended to use Plug and play? As far as I understand it, it allows the operating system ( in my case xp) to assign IRQs to the devices...

This recommended in most cases for Audio Pc's and giga?

I am using RME hardware ( MADI card) with a Asus P4C800 - E deluxe board
Graphics card is a Matrox P650.

Most of my system probs have been fixed by changing bios settings from the default. I've always wondered what most people have the Bios setting for PnP.

Thanks for any input!