Just to share my experience ... I use an M Audio AudioPhile 24/96 card with my GS96. When I first installed it, I continued to get pops, clicks, fuzz -- I called it the Scratchy-Cracklies.
After reformatting the drive 3 times, reinstalling Windows 3 times, replacing most of my hardware ... I finally found the problem came from the ASUS IPanel hardware device I had purchased. As soon as I unplugged the IPanel, the noise went away!!
I understand this may not apply to very many of you, but it was an expensive lesson for me and I hope this humble note will save someone else from the misery I experienced!