I am encountering a new problem w/ GS 3.21. Everytime I start GS3 I get the "run in diagnostic mode?" dialog box. My system is a relatively new and I am trying to optimize it. I have been around and around w/ the "Unknown system error" etc and was trying to fix that problem when this one came up. I really don't even know where to start but here's the system.
ASUS P5B MB
The problem cropped up after having to reinstall the drivers for the RME.