Since getting involved in computer music without really noticing I've been neglecting playing a real instrument and my playing has suffered because of this (ok, I'm a banjo player so maybe it doesn't count).
Recently I started making the effort to practice again, going back to basics and starting with scales etc. At the gig last night I played better than I had done for ages.
So, has sitting in front of a computer affected your playing? Maybe you're a keyboard player and it helps since you're playing anyway? Do you use your score writer or sequencer more than a live instrument?